ea0059oc4.1 | Clinical highlights | SFEBES2018
Lippert Juliane
, Appenzeller Silke
, Liang Raimunde
, Sbiera Silviu
, Kircher Stefan
, Altieri Barbara
, Weigand Isabel
, Riemens Renzo
, Rosenwald Andreas
, Kroiss Matthias
, Rost Simone
, Fassnacht Martin
, Ronchi Cristina
Background: Adrenocortical carcinoma (ACC) has a heterogeneous prognosis and current medical therapies have limited efficacy in its advanced stages. Genome-wide multi-omics-studies identified molecular patterns associated with clinical outcome. Here, we aimed at identifying a molecular signature useful for both personalized prognostic stratification and druggable targets, using methods applicable in clinical routine.Methods: 117 tumor samples from 107 AC...